Madhav Sharma, Ph.D., M.B.A.

Description

Senior Research Scientist — Pediatrics

Georgia Cancer Center

Madhav Sharma, Ph.D. is a member of the Cancer Immunology, Inflammation and Tolerance Program at the Georgia Cancer Center.  Dr. Sharma earned his Ph.D. (1991) from the National Institute of Immunology, (Jawaharlal Nehru University) in New Delhi, India, under the supervision of Dr. GP Talwar.  He also holds a Master of Business Administration (2007) from Augusta State Unviersity.  Dr. Sharma is working as Senior Research Scientist in the Department of Pediatrics in the Medical College of Georgia.

His current research focuses on tumor immunology and molecular mechanisms of immune suppression and tolerance.  Dr. Sharma works with Dr. Munn and is involved in studies of regulation of T-cell activation by tolerogenic dendritic cells and regulatory T-cells (Tregs) in the setting of cancer.  A major focus of the laboratory is the immunoregulatory role of tryptophan metabolism via the enzyme indoleamine 2,3-dioxygenase (IDO).  Dr. Sharma is supported by grants from the National Cancer Institute as Co-Investigator.