David Munn, M.D.

Description

Associate Professor of Medicine

Professor of Pediatrics

Professor of Pathology

Professor of Cellular Biology and Anatomy

Professor of Biochemistry and Molecular Biology

Professor of Graduate Studies

Cancer Immunology, Inflammation and Tolerance Program

Georgia Cancer Center

Dr. David Munn’s current research focuses on tumor immunology and molecular mechanisms of immune suppression and tolerance.  Dr. Munn’s laboratory studies the regulation of T-cell activation by tolerogenic dendritic cells and regulatory T-cells (Tregs) in the setting of cancer.  A major focus of the laboratory is the immunoregulatory role of tryptophan metabolism via the enzyme indoleamine 2,3-dioxygenase (IDO).  Dr. Munn’s research is supported by grants from the National Cancer Institute and through charitable endowments for pediatric oncology research.

Active projects include multiple preclinical and basic-science studies in tumor immunology, enhancement of anti-tumor immune responses and control of regulatory T-cells.