David Munn, M.D.
Associate Professor of Medicine
Professor of Pediatrics
Professor of Pathology
Professor of Cellular Biology and Anatomy
Professor of Biochemistry and Molecular Biology
Professor of Graduate Studies
Cancer Immunology, Inflammation and Tolerance Program
Georgia Cancer Center
Dr. David Munn’s current research focuses on tumor immunology and molecular mechanisms of immune suppression and tolerance. Dr. Munn’s laboratory studies the regulation of T-cell activation by tolerogenic dendritic cells and regulatory T-cells (Tregs) in the setting of cancer. A major focus of the laboratory is the immunoregulatory role of tryptophan metabolism via the enzyme indoleamine 2,3-dioxygenase (IDO). Dr. Munn’s research is supported by grants from the National Cancer Institute and through charitable endowments for pediatric oncology research.
Active projects include multiple preclinical and basic-science studies in tumor immunology, enhancement of anti-tumor immune responses and control of regulatory T-cells.